Download PDF
Synlett 1999; 1999(5): 561-562
DOI: 10.1055/s-1999-11454
letter
© Georg Thieme Verlag, Rüdigerstr. 14, 70469 Stuttgart, Germany. All rights reserved. This journal, including all individual contributions and illustrations published therein, is legally protected by copyright for the duration of the copyright period. Any use, exploitation or commercialization outside the narrow limits set by copyright legislation, without the publisher's consent, is illegal and liable to criminal prosecution. This applies in particular to photostat reproduction, copying, cyclostyling, mimeographing or duplication of any kind, translating, preparation of microfilms, and electronic data processing and storage.

Ti(II)-Mediated Cyclization of ω-Vinylimides. A Stereoselective Approach to Gelsemine

Moo Je Sung* , Chi-Wan Lee, Jin Kun Cha
  • *Department of Chemistry, University of Alabama, Tuscaloosa, AL 35487, USA; Fax +1(2 05)3 48-91 04; E-mail: cha@jkc.ch.ua.edu
Further Information

Publication History

Publication Date:
31 December 1999 (online)

  PDF Download  Permissions and Reprints All articles of this category

A convenient approach to the synthetically challenging tricyclic core of gelsemine (1) has been developed by the titanium-mediated intramolecular coupling of bicyclic ω-vinylimides.

alkaloid synthesis - gelsemine - titanium-mediated cyclization - ω-vinylimides - N-acylaminals

      >