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Synlett 1998; 1998(7): 733-734
DOI: 10.1055/s-1998-1767
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Addition of Allylmagnesium Bromide to ROPHy/SOPHy Aldoximes: Asymmetric Synthesis of Protected β-Amino Acids

Christopher J. Moody* , James C. A. Hunt
  • *Department of Chemistry, University of Exeter, Stocker Road, Exeter, EX4 4QD, U.K.
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Publication Date:
31 December 2000 (online)

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A new asymmetric synthesis of protected β-amino acids is described in which the key step is the diastereoselective addition of allylmagnesium bromide to O-(1-phenylbutyl) aldoximes.

oxime ether - hydroxylamine - homoallylamine - β-amino acid

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