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Synthesis 1997; 1997(11): 1246-1248
DOI: 10.1055/s-1997-1348
short paper
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A Facile Synthesis of 6-C-Prenylflavanones

Xianyong Bu, Lianyun Zhao, Yulin Li*
  • *National Laboratory of Applied Organic Chemistry and Institute of Organic Chemistry, Lanzhou University, Lanzhou 730000, People’s Republic of China, Fax +86(931)8911100; E-mail: liyl@lzu.edu.cn
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Publication History

Publication Date:
31 December 2000 (online)

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The first total synthesis of two natural 6-C-prenylflavanones, (±)-6-C-prenyleriodoctyol (1) and 6-C-prenylnaringenin (2), using the acetophenone derivative 6 as the key intermediate is described. This new efficient synthetic approach was mainly based on Claisen rearrangement and cyclization reaction.

6-C-prenylflavanones - Claisen rearrangement - cyclization 2,4-bis(methoxymethoxy)-6-hydroxy-3-prenylacetophenone

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