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Synthesis 1997; 1997(10): 1131-1133
DOI: 10.1055/s-1997-1325
DOI: 10.1055/s-1997-1325
short paper
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Synthesis of 7,8-Dimethoxy-2-oxo-1,3,4,5-tetrahydropyrrolo[4,3,2-de]quinoline: A Key Intermediate en Route to Makaluvamines, Discorhabdin C and Other Marine Alkaloids of this Group via Vicarious Nucleophilic Substitution of Hydrogen
Further Information
Publication History
Publication Date:
31 December 2000 (online)
The title compound 1a, a key intermediate in synthesis of an important group of alkaloids, is efficiently prepared via vicarious nucleophilic substitution of hydrogen followed by simple transformations.
vicarious nucleophilic substitution - selective NO2 hydrogenation - marine alkaloids precursor