Download PDF
Synthesis 1997; 1997(3): 287-289
DOI: 10.1055/s-1997-1177
short paper
© Georg Thieme Verlag, Rüdigerstr. 14, 70469 Stuttgart, Germany. All rights reserved. This journal, including all individual contributions and illustrations published therein, is legally protected by copyright for the duration of the copyright period. Any use, exploitation or commercialization outside the narrow limits set by copyright legislation, without the publisher's consent, is illegal and liable to criminal prosecution. This applies in particular to photostat reproduction, copying, cyclostyling, mimeographing or duplication of any kind, translating, preparation of microfilms, and electronic data processing and storage.

Convenient Preparation of 4-Alkylidene-1H-imidazol-5(4H)-one Derivatives from Imidate and Aldehydes by a Solvent-Free Cycloaddition under Microwaves

Ghislaine Kerneur, Jean Michel Lerestif, Jean Pierre Bazureau* , Jack Hamelin
  • *Groupe de Recherches de Physico-Chimie Structurale 3, URA au CNRS N°704, Université de Rennes 1, Campus de Beaulieu, F-35042 Rennes Cédex, France, Fax +33(99)286374; E-mail Jean-Pierre.Bazureau@univ-rennes1.fr
Further Information

Publication History

Publication Date:
31 December 2000 (online)

  PDF Download  Permissions and Reprints All articles of this category

4-Alkylidene-1H-imidazol-5(4H)-one derivatives 4 (aromatic, aliphatic and heteroaromatic) are obtained in good to excellent yields by 1,3-dipolar cycloaddition by using solvent-free conditions under microwave irradiation from imidate 1, aldehydes 2 and dry acetic acid as catalyst. Similar cycloadducts 4 were obtained by cycloaddition from imidate 1 and aldimines 3 as dipolarophiles under microwaves.

1,3-dipolar cycloaddition - imidate - aldehydes - 4-alkylidene-1H-imidazol-5(4H)-one - microwave irradiation

      >