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Synlett 1995; 1995(SI): 523-524
DOI: 10.1055/s-1995-5291
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p-Methoxybenzyl Ethers as Acid-Labile Protecting Groups in Oligosaccharide Synthesis

Lin Yan, Daniel Kahne*
  • *Department of Chemistry, Princeton University, Princeton, New Jersey 08544, USA
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Publication Date:
31 December 2000 (online)

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The p-methoxybenzyl (PMB) group can be removed selectively with trifluoroacetic acid (TFA) in the presence of multiple glycosidic linkages as well as other sensitive functionality used in oligosaccharide synthesis.

p-Methoxybenzyl ethers - oligosaccharides - sulfoxide method - trifluoroacetic acid deprotection

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