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Synlett 1995; 1995(6): 643-644
DOI: 10.1055/s-1995-5017
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Direct Esterification of Phosphonic Acid Salts Using the Mitsunobu Reaction

Mourad Saady1 , Luc Lebeau1 , Charles Mioskowski2
  • 1Université Louis Pasteur - Faculté de Pharmacie - Laboratoire de Synthèse Bioorganique associé au CNRS - 74, route du Rhin - BP 24 - 67401 Illkirch - France
  • 2Université Louis Pasteur - Faculté de Pharmacie - Laboratoire de Synthèse Bioorganique associé au CNRS - 74, route du Rhin - BP 24 - 67401 Illkirch - France
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Publication History

Publication Date:
31 December 2000 (online)

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For the first time, phosphonic acid salts are condensed in good yields with various alcohols, including nucleosides, using a modified protocol of the Mitsunobu reaction.

Phosphonate - Mitsunobu reaction - esterification - nucleotide

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