Download PDF
Synlett 1995; 1995(1): 101-102
DOI: 10.1055/s-1995-4844
letter
© Georg Thieme Verlag, Rüdigerstr. 14, 70469 Stuttgart, Germany. All rights reserved. This journal, including all individual contributions and illustrations published therein, is legally protected by copyright for the duration of the copyright period. Any use, exploitation or commercialization outside the narrow limits set by copyright legislation, without the publisher's consent, is illegal and liable to criminal prosecution. This applies in particular to photostat reproduction, copying, cyclostyling, mimeographing or duplication of any kind, translating, preparation of microfilms, and electronic data processing and storage.

Synthesis of Bridged Bicyclic β-Trifluoroacetoxy β-Trifluoromethyl α-Amino Acid Derivatives by an Original Dakin-West/Diels-Alder Tandem Sequence

Thierry Cufos, Philippe Diaz, Lucien Stella*
  • *Université d’Aix-Marseille III, Laboratoire de Chimie Moléculaire Organique, associé au CNRS, 13397 Marseille Cédex 20, France
Further Information

Publication History

Publication Date:
31 December 2000 (online)

  PDF Download  Permissions and Reprints All articles of this category

The reaction of hippuric acid with trifluoroacetic anhydride in the presence of cyclopentadiene affords useful bicyclic α-amino acid derivatives bearing β-trifluoroacetoxy and β-trifluoromethyl groups.

β-trifluoromethyl α-amino acids - Diels-Alder cycloaddition - Dakin-West reaction - 2-phenyl-5-oxazolone - tandem sequence

      >