Synthesis of 3,4-Dihydroisocoumarins via Palladium-Catalyzed Coupling of Vinylic Halides or Triflates with o-(1-Alkenyl)benzoic Acids

Richard C. Larock; Hoseok Yang

doi:10.1055/s-1994-22996

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Synlett 1994; 1994(9): 748-750
DOI: 10.1055/s-1994-22996

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Synthesis of 3,4-Dihydroisocoumarins via Palladium-Catalyzed Coupling of Vinylic Halides or Triflates with o-(1-Alkenyl)benzoic Acids

Richard C. Larock^* , Hoseok Yang

^*Department of Chemistry, Iowa State University, Ames, Iowa 50011 USA

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Publication Date:
18 September 2002 (online)

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3,4-Dihydroisocoumarins are readily prepared in high yield by the palladium-catalyzed coupling of o-(1-alkenyl)benzoic acids with vinylic halides or triflates.

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