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Synlett 1994; 1994(3): 181-182
DOI: 10.1055/s-1994-22785
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Alkenyl Stannane-Allylic Halide Macrocyclisations. An Approach to Amphidinolide A and Related Polyolefin Macrolide Systems

Christopher Boden* , Gerald Pattenden
  • *Department of Chemistry, The University, Nottingham NG7 2RD, United Kingdom
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Publication Date:
22 March 2002 (online)

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A synthetic approach to polyolefin macrolides based on intramolecular Stille-type coupling reactions between alkenyl stannanes and allylic chlorides is described, e.g. 8 → 10, 11 → 12.

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