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Synlett 1992; 1992(12): 1005-1006
DOI: 10.1055/s-1992-21564
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An Improved Synthesis of the Aranorosin Nucleus

Alexander McKillop* , Richard J. K. Taylor, Robert J. Watson, Norman Lewis
  • *School of Chemical Sciences, University of East Anglia, Norwich NR4 7TJ, England
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Publication Date:
08 March 2002 (online)

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An improved synthesis of the tetracyclic aranorosin nucleus (2) is described proceeding via an unusually stable ozonide (1,2,4-trioxolane), in the key step. The structure of (2) has been confirmed by X-ray crystallography.

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