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Synlett 1992; 1992(10): 793-795
DOI: 10.1055/s-1992-21492
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Use of an Alanine Derived ß-Ketosulfone in the Synthesis of Peptide Isosteres

Barry Lygo*
  • *Department of Chemistry and Applied Chemistry, University of Salford M5 4WT, England
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Publication Date:
08 March 2002 (online)

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The utility of alanine derived ß-ketosulfones in the synthesis of a range of peptide isosteres is investigated. The method is used to prepare di- and tri-peptide systems incorporating isosteric Ala-Gly units.

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