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Synlett 1992; 1992(3): 249-251
DOI: 10.1055/s-1992-21332
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Comments on the Use of Diphenyloxazinone Derivatives as Glycine Anion Templates for Amino Acid Synthesis

Jack E. Baldwin* , Victor Lee, Christopher J. Schofield
  • *The Dyson Perrins Laboratory and the Oxford Centre for Molecular Sciences, South Parks Road, Oxford OX1 3QY, England
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Publication Date:
08 March 2002 (online)

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Some observations resulting from the use of optically active diphenyloxazinone derivatives 1 and 4 as glycine anion equivalents are reported. The utility of the method is demonstrated in the synthesis of (S,S)-2,6-diamino-2-hydroxymethylheptanedioic acid (7).

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