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Synlett 1992; 1992(3): 231-232
DOI: 10.1055/s-1992-21323
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Isoxazolo [4,3-c] quinolines from o-Azidobenzonitrile Oxide by Sequential Carbanion Attack and Intramolecular Aza-Wittig Reaction

Bambang Purwono* , Robert K. Smalley, Thomas C. Porter
  • *Department of Chemistry and Applied Chemistry, University of Salford, Salford M5 4WT, England
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Publication Date:
08 March 2002 (online)

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3-(o-Azidophenyl)isoxazoles (3) derived from o-azidobenzonitrile oxide and carbanions, on treatment with triphenylphosphine in toluene undergo cyclisation via an aza-Wittig reaction to 3,4-disubstituted isoxazolo [4,3-c]quinolines (5).

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