Download PDF
Synlett 1991; 1991(7): 515-516
DOI: 10.1055/s-1991-20784
letter
© Georg Thieme Verlag, Rüdigerstr. 14, 70469 Stuttgart, Germany. All rights reserved. This journal, including all individual contributions and illustrations published therein, is legally protected by copyright for the duration of the copyright period. Any use, exploitation or commercialization outside the narrow limits set by copyright legislation, without the publisher's consent, is illegal and liable to criminal prosecution. This applies in particular to photostat reproduction, copying, cyclostyling, mimeographing or duplication of any kind, translating, preparation of microfilms, and electronic data processing and storage.

Kinetic Resolution of Chiral Imidazolidinones Using Homochiral Lithium Amide Bases

Peter Coggins* , Nigel S. Simpkins
  • *Department of Chemistry, University of Nottingham, University Park, Nottingham, NG7 2RD, England
Further Information

Publication History

Publication Date:
07 March 2002 (online)

  PDF Download  Permissions and Reprints All articles of this category

A racemic imidazolidinone (1-tert-butoxycarbonyl-2-tert-butyl-3-methyl-4-imidazolidinone) has been subjected to kinetic resolution using a homochiral lithium amide base [lithium (R,R)-bis(1-phenylethyl)amide], thus enabling access to the optically active material in up to 80 % enantiomeric excess.

      >