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Synlett 1990; 1990(12): 743-744
DOI: 10.1055/s-1990-21234
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A Concise and Stereoselective Synthesis of (+)-12-n-Butyldeoxoartemisinin

Mankil Jung* , Daniel A. Bustos, Hala N. ElSohly, James D. McChesney
  • *Research Institute of Pharmaceutical Sciences, School of Pharmacy, University of Mississippi, University, Mississippi 38677, USA and Department of Medicinal Chemistry, School of Pharmacy, University of Mississippi, University, Mississippi 38677, USA
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Publication History

Publication Date:
08 March 2002 (online)

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(+)-Artemisinic (qinghao) acid was converted into (+)-12-n-butyl-12-deoxoartemisinin (12-butyl-12-deoxoqinghaosu) via photoxidative cyclization as a key step.

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