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Synlett 1990; 1990(1): 36-37
DOI: 10.1055/s-1990-20977
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Synthesis of the Tris-oxazole Ring System of Ulapualides

David W. Knight* , Gerald Pattenden, David E. Rippon
  • *Department of Chemistry, The University, Nottingham NG7 2RD, England
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Publication Date:
08 March 2002 (online)

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Using three molecules of serine, three sequential oxazoline cyclisation-oxidation reactions, i.e. 2→5, 7→9, 10→11, are used to elaborate the novel tris-oxazole ring system found in the ulapualide family, e.g. 1, of marine metabolites.

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