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Synthesis 1989; 1989(11): 873-874
DOI: 10.1055/s-1989-27419
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Synthesis of 2-Aryl- and 5-Alkyl-2-aryloxazoles from 2-Aryl-5-bromooxazoles

Choji Kashima* , Hideki Arao
  • *Department of Chemistry, University of Tsukuba, Tsukuba, Ibaraki 305, Japan
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Publication Date:
02 May 2002 (online)

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2-Aryloxazoles, their 5-deuterio derivatives, and 5-alkyl-2-aryloxazoles are prepared in good yields from 2-aryl-5-bromooxazoles via halogen/metal exchange with butyllithium followed by treatment with water, methanol-O-d, or alkyl halides, respectively.

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