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Synthesis 1989; 1989(3): 230-232
DOI: 10.1055/s-1989-27213
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A Very Efficient, Short Synthesis of 6,7,8,8a-Tetrahydropyrrolo[1,2-a]pyrimidines from lmines via 4-Amino-1-aza-butadienes

José Barluenga* , Miguel Tomás, Jesús Jardón, Eduardo Rubio, Vicente Gotor
  • *Departamento de Química Organometálica, Universidad de Oviedo, E- 33071 Oviedo, Spain
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Publication Date:
17 September 2002 (online)

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N-Substituted imines are transformed into 6,7,8,8a-tetrahydropyrrolo [1,2-a]pyrimidines by base-catalyzed reaction with a nitrile, followed by treatment with aqueous acid at room temperature.

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