Synthesis 1989; 1989(2): 131-132
DOI: 10.1055/s-1989-27173
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Copper(I) Chloride Catalyzed Addition of Alcohols to Alkyl lsocyanates. A Mild and Expedient Method for Alkyl Carbamate Formation

M. E. Duggan* , J. S. Imagire
  • *Merck Sharp & Dohme Research Laboratories, West Point, PA 19486, USA
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Publication History

Publication Date:
17 September 2002 (online)

Treatment of alkyl isocyanates with copper(I) chloride in the presence of primary, secondary or tertiary alcohols provides a mild and efficient method for alkyl carbamate formation.

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