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Synthesis 1989; 1989(1): 53-54
DOI: 10.1055/s-1989-27150
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Synthesis of the 3′,5′-Cyclic Phosphates from Unprotected Nucleosides

H. -G. Genieser* , E. Butt, U. Bottin, W. Dostmann, B. Jastorff
  • *Institut für Organische Chemie, Universität Bremen, D-2800 Bremen 33, Federal Republic of Germany
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Publication History

Publication Date:
27 September 2002 (online)

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Unprotected nucleosides were phosphorylated with phosphoryl chloride in trialkyl phosphates and subsequently cyclized with base to give 3′,5′-cyclic nucleotides in good yields.

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