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Synthesis 1988; 1988(9): 710-712
DOI: 10.1055/s-1988-27681
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Desilylation of tert-Butyldimethylsilyl Ethers of Phenols

Achintya K. Sinhababu* , Masami Kawase, Ronald T. Borchardt
  • *Departments of Medicinal and Pharmaceutical Chemistry, School of Pharmacy, University of Kansas, Lawrence, KS 66045, USA
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Publication Date:
18 September 2002 (online)

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Treatment of tert-butyldimethylsilyl ethers of phenols and diphenols with potassium fluoride in the presence of catalytic amounts of hydrobromic acid in dimethylformamide generates the corresponding phenols or diphenols in high yields.

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