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Synthesis 1987; 1987(12): 1128-1130
DOI: 10.1055/s-1987-28197
DOI: 10.1055/s-1987-28197
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Reduction of Lactams to Cyclic Tertiary Amines by Sodium Borohydride
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Publication History
Publication Date:
20 August 2002 (online)
Sodium borohydride in boiling tert-butyl alcohol/methanol reduces tertiary δ-lactams of the quinolizidine type to the corresponding amines in high yield.