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Synthesis 1987; 1987(5): 511-512
DOI: 10.1055/s-1987-27988
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A New and Efficient One-Pot Preparation of Alkyl Halides From Alcohols

Francisco Camps* , Vicens Gasol, Angel Guerrero
  • *Departamento de Química Orgánica Biológica, C.I.D. (CSIC), Jorge Girona Salgado, 18-26, E-08034-Barcelona, Spain
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Publication History

Publication Date:
18 September 2002 (online)

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Primary alkanols and 2-alkenols are converted into the corresponding halides in high yield by a one-pot, two-step reaction via transformation into intermediate trifluoroacetates followed by nucleophilic substitution with lithium halides.

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