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Synthesis 1987; 1987(4): 397-399
DOI: 10.1055/s-1987-27961
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A Simple One-Pot Synthesis of Acylated Cyanohydrins of 3-Indolecarbaldehydes

Takushi Kurihara* , Toshiro Fujimoto, Shinya Harusawa, Ryuji Yoneda
  • *Osaka University of Pharmaceutical Sciences, 2-10-65, Kawai, Matsubara, Osaka 580, Japan
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Publication Date:
20 August 2002 (online)

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Reaction of 3-indolecarbaldehydes with a variety of acylchlorides in the presence of lithium cyanide to give 1-acyl-3-(α-acyloxy)indoleacetonitriles is described.

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