Download PDF
Synthesis 1987; 1987(3): 321-323
DOI: 10.1055/s-1987-27935
communication
© Georg Thieme Verlag, Rüdigerstr. 14, 70469 Stuttgart, Germany. All rights reserved. This journal, including all individual contributions and illustrations published therein, is legally protected by copyright for the duration of the copyright period. Any use, exploitation or commercialization outside the narrow limits set by copyright legislation, without the publisher's consent, is illegal and liable to criminal prosecution. This applies in particular to photostat reproduction, copying, cyclostyling, mimeographing or duplication of any kind, translating, preparation of microfilms, and electronic data processing and storage.

Synthese von Brückenkopf-Derivaten; 1. Herstellung von substituierten Bicyclo[2.2.1]heptan-1-olen und zugehörigen Trifluormethansulfonaten

A. García Martínez* , E. Teso Vilar, A. García Fraile, C. Ruano Franco, J. Soto Salvador, L. R. Subramanian, Michael Hanack
  • *Departamento de Química Orgánica, Facultad de Ciencias Químicas, Universidad Complutense, Ciudad Universitaria, E-28040 Madrid, Spain
Further Information

Publication History

Publication Date:
12 September 2002 (online)

  PDF Download  Permissions and Reprints All articles of this category

Synthesis of Bridgehead Derivatives; 1. Preparation of Substituted Bicyclo[2.2.1]heptan-1-ols and the Corresponding Trifluoromethanesulfonates The reaction of substituted bicyclo[2.2.1]heptan-2-ones 1 with trifluoromethanesulfonic anhydride (Tf2O) yields bridgehead trifluoromethanesulfonates (triflates, 2). Both the reduction with lithium aluminum hydride and the alkaline hydrolysis of 2 affords the corresponding bridgehead alcohols 3 in good yields.

      >