Download PDF
Synthesis 1987; 1987(3): 236-241
DOI: 10.1055/s-1987-27900
paper
© Georg Thieme Verlag, Rüdigerstr. 14, 70469 Stuttgart, Germany. All rights reserved. This journal, including all individual contributions and illustrations published therein, is legally protected by copyright for the duration of the copyright period. Any use, exploitation or commercialization outside the narrow limits set by copyright legislation, without the publisher's consent, is illegal and liable to criminal prosecution. This applies in particular to photostat reproduction, copying, cyclostyling, mimeographing or duplication of any kind, translating, preparation of microfilms, and electronic data processing and storage.

Amino Acids and Peptides; 60.1 Synthesis of Biologically Active Cyclopeptides; 10. Synthesis of 16 Structural Isomers of Dolastatin 3; II:2 Synthesis of the Linear Educts and the Cyclopeptides

Ulrich Schmidt* , Roland Utz, Albrecht Lieberknecht, Helmut Griesser, Bernd Potzolli, Johanna Bahr, Karin Wagner, Peter Fischer
  • *Institut für Organische Chemie, Biochemie und Isotopenforschung der Universität Stuttgart, Pfaffenwaldring 55, D-7000 Stuttgart 80, West Germany
Further Information

Publication History

Publication Date:
12 September 2002 (online)

  PDF Download  Permissions and Reprints All articles of this category

Sixteen isomers of the cancerostatic cyclopeptide Dolastatin 3 of marine origin are synthesized. The proposed structure of Dolastatin 3 is proved to be not correct.

      >