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Synthesis 1986; 1986(12): 1054-1055
DOI: 10.1055/s-1986-31873
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A Simple One-Pot Synthesis of Silylated and Acylated Cyanohydrins

Ryuji Yoneda* , Kazunori Santo, Shinya Harusawa, Takushi Kurihara
  • *Osaka University of Pharmaceutical Sciences, 2-10-65, Kawai, Matsubara, Osaka 580, Japan
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Publication Date:
12 September 2002 (online)

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Reaction of variety of aldehydes and ketones with chlorotrimethylsilane and acyl chlorides in the presence of lithium cyanide to give trimethylsilylcyanohydrins and acylcyanohydrins is described.

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