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Synthesis 1986; 1986(10): 864-865
DOI: 10.1055/s-1986-31810
DOI: 10.1055/s-1986-31810
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A New, Facile Synthesis of 4-Alkyl- and Aryl-Substituted 3-Amino-4H-1,2,4-benzothiadiazine 1,1-Dioxides
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Publication History
Publication Date:
20 August 2002 (online)
A new efficient preparation of 4-alkyl- and aryl-substituted 3-amino- 4H-1,2,4-benzothiadiazine 1,1-dioxides (3) is described via the 3-chloro derivatives of 4-alkyl- and aryl substituted 3-oxo-2H-3,4-dihydro-1,2,4-benzothiadiazine 1,1-dioxides, (1) on their treatment with aqueous ammonia solution.