Synthesis 1986; 1986(4): 338-340
DOI: 10.1055/s-1986-31609
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Lithium Aluminum Hydride Reductions; A New Hydrolysis Method for Intractable Products

John Powell* , Nadine James, Stuart J. Smith
  • *Lash Miller Chemical Laboratories, University of Toronto, Toronto, Ontario, Canada, M5S 1A1
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Publication History

Publication Date:
27 September 2002 (online)

A new hydrolysis procedure is described for lithium aluminum hydride reductions which allows for simpler technique and markedly improved yields in the synthesis of multifunctional products. The procedure is illustrated by the reduction of a series of formamides and amino-esters to give various propanolamines.

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