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Synthesis 1986; 1986(1): 76-78
DOI: 10.1055/s-1986-31485
DOI: 10.1055/s-1986-31485
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The Synthesis of Quinolines from N-Alkylformanilides and Activated Acetic Acids
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Publication Date:
20 August 2002 (online)
The action of phosphoryl chloride and N-methylformanilide on activated acetic acids (X-CH2-COOH) or acetyl chlorides (X-CH2-CO-Cl), whereX = aryl, cyano, or methoxycarbonyl, yields N-methylquinolinium salts orquinolones in good yields.