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Klin Monbl Augenheilkd 2018; 235(04): 480-482
DOI: 10.1055/s-0043-123641
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Georg Thieme Verlag KG Stuttgart · New York

Sjögrenʼs Disease Associated with Severe Retinal Vasculitis and/or Necrotizing Scleritis: Two Cases

Morbus-Sjögren-assoziierte schwere retinale Vaskulitis und/oder nekrotisierende Skleritis: 2 Fälle
Sophie Lopez Baumann
1   Ophthalmology, Jules-Gonin Eye Hospital, University of Lausanne, Lausanne, Switzerland
,
Amelie Borgeat Kaeser
2   Immunology and Allergology Department, CHUV, University of Lausanne, Lausanne, Switzerland
,
Flore Valerio
2   Immunology and Allergology Department, CHUV, University of Lausanne, Lausanne, Switzerland
,
Francois Spertini
2   Immunology and Allergology Department, CHUV, University of Lausanne, Lausanne, Switzerland
,
Yan Guex-Crosier
1   Ophthalmology, Jules-Gonin Eye Hospital, University of Lausanne, Lausanne, Switzerland
› Author Affiliations
Further Information

Publication History

received 17 September 2017

accepted 10 November 2017

Publication Date:
16 February 2018 (online)

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Introduction

Sjögrenʼs syndrome is a systemic autoimmune disease with numerous manifestations as it can affect the entire body, which, in turn, makes a diagnosis difficult. It is characterized by lymphocytic infiltration of the salivary and lacrimal glands, which results in sicca syndrome. Depending on the severity of the damaged gland, symptoms such as xerophtalmia, xerostomia, or dry skin can be more or less important. The diagnosis is based on the AECG (American-European Consensus Group) consensus criteria with the presence of a nodular salivary gland infiltration of grade III or the presence of anti-SS-A (Ro) (Anti-Sjögrenʼs-syndrome-related antigen A) or anti-SS-B (La) (Anti-Sjögrenʼs-syndrome-related antigen B) antibodies [1].

 

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