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Int J Angiol 2022; 31(04): 284-288
DOI: 10.1055/s-0042-1743253
Original Article

Complex Arterial Pathology of Angiomyolipomas of Tuberous Sclerosis

Christopher D. Yeisley
1   Division of Interventional Radiology, Northwell Health, Great Neck, New York
,
Shima Tafreshi 
1   Division of Interventional Radiology, Northwell Health, Great Neck, New York
,
Joseph Moirano
2   Zucker School of Medicine at Hofstra/Northwell, Hempstead, New York
,
Eric Gandras
1   Division of Interventional Radiology, Northwell Health, Great Neck, New York
,
David Siegel
1   Division of Interventional Radiology, Northwell Health, Great Neck, New York
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Abstract

Based on observations at angiography, it was hypothesized that angiomyolipomas (AMLs) associated with tuberous sclerosis complex (TSC) have a more robust parasitic blood supply and require more complex embolization involving lower order vessels compared with the non-TSC patients' AMLs. This was a retrospective review of 71 patients who underwent angiography and embolization for renal AML at multiple centers within a single health system. All of the patients with TSC (11/11) were found to have “complex” tumor vascular supply. Of the patients with sporadic AML, 51/60 (85%) had “simple” tumor vascular supply. Sporadic cases with a complex tumor blood supply were larger tumors, with an average size of 11.5 cm. This study supports our hypothesis that AMLs associated with TSC have more complex tumor vascularity compared with sporadic lesions, and aims to better prepare interventionalists to deal with the complex cases.

Keywords

AML - tuberous sclerosis - tuberous sclerosis complex - tumor - embolization - complex tumor vascularity - hemorrhage

Financial Disclosures

Dr. Gandras reports other from Instylla Inc., personal fees from Teleflex, outside the submitted work.




Publication History

Article published online:
13 April 2022

© 2022. International College of Angiology. This article is published by Thieme.

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