Dtsch Med Wochenschr 2016; 141(1): 51-57
DOI: 10.1055/s-0041-102893
Fachwissen
Übersicht
© Georg Thieme Verlag KG Stuttgart · New York

Update HIV und Neurologie

Update HIV and neurology
Katrin Hahn
1   Klinik für Neurologie, Charité Berlin
,
Matthias Maschke
2   Klinik für Neurologie, Krankenhaus der Barmherzigen Brüder Trier
,
Christian Eggers
3   Abteilung für Neurologie, Krankenhaus der Barmherzigen Brüder Linz
,
Ingo Wilhelm Husstedt
4   Praxis im Krankenhaus Maria Frieden, Telgte / Medizinische Fakultät der Westfälischen Wilhelms Universität Münster
,
Gabriele Arendt
5   Klinik für Neurologie, Universitätsklinikum Düsseldorf
› Author Affiliations
Further Information

Publication History

Publication Date:
28 December 2015 (online)

Zusammenfassung

Die Fortschritte der antiretroviralen Therapie haben die HIV-Infektion zu einer chronischen Krankheit gemacht. Der Übersichtsartikel fasst zusammen, was ein Leben mit HIV aus neurologischer Sicht über Jahrzehnte hinweg für die Betroffenen bedeutet. Neben klinischen und pathophysiologischen Aspekten des HIV-assoziierten kognitiven Defizits (HAND) werden auch periphere HIV-Manifestationen beleuchtet. Der Artikel berücksichtigt Komorbiditäten wie die in der Inzidenz ansteigende Neurolues, sowie die Hepatitis C, da beide durch ihr Interaktionsspektrum mit dem HI-Virus insbesondere für den Neurologen von großem Interesse sind.

Abstract

With modern antiretroviral drug regimens, HIV-infected people are living longer and HIV has transformed into a chronic illness. The review summarizes pathophysiological as well as clinical aspects of a chronic infection from a neurological point of view including neurocognitive impairment, depression, neuropathies and myopathies. It also draws attention to comorbidities such as syphilis and hepatitis C. They are of particular neurological interest because of the interaction of the pathogens.

 
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