Eur J Pediatr Surg 2020; 30(01): 111-116
DOI: 10.1055/s-0039-3402713
Original Article
Georg Thieme Verlag KG Stuttgart · New York

Indications, Surgical Complications, and Long-Term Outcomes in Pediatric Esophageal Reconstructions with Pedicled Jejunal Interposition Graft

Antti Koivusalo
1   Department of Pediatric Surgery, Children's Hospital, University of Helsinki, Helsinki, Finland
,
Janne Suominen
1   Department of Pediatric Surgery, Children's Hospital, University of Helsinki, Helsinki, Finland
,
Jukka Salminen
2   Department of Pediatric Cardiac Surgery, Children's Hospital, University of Helsinki, Helsinki, Finland
,
Mikko Pakarinen
1   Department of Pediatric Surgery, Children's Hospital, University of Helsinki, Helsinki, Finland
› Author Affiliations
Further Information

Publication History

13 May 2019

03 December 2019

Publication Date:
01 January 2020 (online)

Abstract

Introduction Several surgical techniques are available for pediatric esophageal reconstruction. We started to use pedicled jejunum interposition graft (PJIG) because other techniques had significant long-term complications. In this retrospective study, the indications, surgical complications, and long-term outcomes were assessed in patients with PJIG.

Materials and Methods With ethical consent, we reviewed the hospital records of 14 patients (7 females) who from 2005 to 2019 underwent a total of 16 esophageal reconstructions with PJIG.

Results Median age at PJIG was 1.6 (range: 0.2–15) years. Underlying conditions were esophageal atresia (EA) (n = 11) or native esophagus lost by trauma or infection (n = 3). Eight patients with EA underwent PJIG as primary reconstruction and three as a rescue operation after complications in primary repair. Significant surgical complications occurred in 43% of patients. Major reoperations in six (43%) patients included resection and reanastomosis of strictured proximal PJIG (n = 1) and redo PJIG after failure of the first operation (n = 2). Surgical mortality was nil. After a median follow-up of 6.5 (range: 0.7–14) years, 13 (93%) patients survived, and 1 died of congenital heart disease. PJIG failed in three (23%) survivors of whom two underwent graft removal because of life-threatening aspiration and one did not start oral feeds at all. Ten survivors (77%) have full enteral feeds. Respiratory function in the survivors is satisfactory. Two patients have moderate and three mild gastroesophageal reflux symptoms.

Conclusion PJIG was a functional option for a variety of conditions that required esophageal reconstruction. However, significant early and late complications required major surgical revisions.

 
  • References

  • 1 Koivusalo AI, Sistonen SJ, Lindahl HG, Rintala RJ, Pakarinen MP. Long-term outcomes of oesophageal atresia without or with proximal tracheooesophageal fistula - Gross types A and B. J Pediatr Surg 2017; 52 (10) 1571-1575
  • 2 Bairdain S, Hamilton TE, Smithers CJ. , et al. Foker process for the correction of long gap esophageal atresia: primary treatment versus secondary treatment after prior esophageal surgery. J Pediatr Surg 2015; 50 (06) 933-937
  • 3 van der Zee DC, Gallo G, Tytgat SH. Thoracoscopic traction technique in long gap esophageal atresia: entering a new era. Surg Endosc 2015; 29 (11) 3324-3330
  • 4 Heimlich HJ. Reversed gastric tube (RGT) esophagoplasty for failure of colon, jejunum and prosthetic interpositions. Ann Surg 1975; 182 (02) 154-160
  • 5 Bax NM, van der Zee DC. Jejunal pedicle grafts for reconstruction of the esophagus in children. J Pediatr Surg 2007; 42 (02) 363-369
  • 6 Katsura S, Ishikawa Y, Okayama G. Transplantation of the partially resected middle esophagus with a jejunal graft. Ann Surg 1958; 147 (02) 146-156
  • 7 Hetzel DJ, Dent J, Reed WD. , et al. Healing and relapse of severe peptic esophagitis after treatment with omeprazole. Gastroenterology 1988; 95 (04) 903-912
  • 8 Ismail-Beigi F, Horton PF, Pope II CE. Histological consequences of gastroesophageal reflux in man. Gastroenterology 1970; 58 (02) 163-174
  • 9 Kunisaki SM, Coran AG. Esophageal replacement. Semin Pediatr Surg 2017; 26 (02) 105-115
  • 10 Nakamura T, Inokuchi K, Sugimachi K. Use of revascularized jejunum as a free graft for cervical esophagus. Jpn J Surg 1975; 5 (02) 92-102
  • 11 Gallo G, Zwaveling S, Groen H, Van der Zee D, Hulscher J. Long-gap esophageal atresia: a meta-analysis of jejunal interposition, colon interposition, and gastric pull-up. Eur J Pediatr Surg 2012; 22 (06) 420-425
  • 12 Gallo G, Zwaveling S, Van der Zee DC, Bax KN, de Langen ZJ, Hulscher JB. A two-center comparative study of gastric pull-up and jejunal interposition for long gap esophageal atresia. J Pediatr Surg 2015; 50 (04) 535-539
  • 13 Bax NM, Van Renterghem KM. Ileal pedicle grafting for esophageal replacement in children. Pediatr Surg Int 2005; 21 (05) 369-372
  • 14 Gallo G, Vrijlandt EJLE, Arets HGM. , et al. Respiratory function after esophageal replacement in children. J Pediatr Surg 2017; 52 (11) 1736-1741
  • 15 Awad K, Jaffray B. Oesophageal replacement with stomach: a personal series and review of published experience. J Paediatr Child Health 2017; 53 (12) 1159-1166