Am J Perinatol 2021; 38(07): 714-720
DOI: 10.1055/s-0039-3400997
Original Article

Outpatient Expectant Management of Term Prelabor Rupture of Membranes: A Retrospective Cohort Study

1   Department of Obstetrics, Gynecology, and Reproductive Biology, Massachusetts General Hospital, Boston, Massachusetts
2   Harvard Medical School, Harvard University, Boston, Massachusetts
,
Allison S. Bryant Mantha
1   Department of Obstetrics, Gynecology, and Reproductive Biology, Massachusetts General Hospital, Boston, Massachusetts
2   Harvard Medical School, Harvard University, Boston, Massachusetts
,
Mark A. Clapp
1   Department of Obstetrics, Gynecology, and Reproductive Biology, Massachusetts General Hospital, Boston, Massachusetts
2   Harvard Medical School, Harvard University, Boston, Massachusetts
› Author Affiliations
Funding None.

Abstract

Objective To examine outcomes among women with prelabor rupture of membranes (PROM) who declined induction and chose outpatient expectant management compared with those admitted for induction.

Study Design This is a retrospective cohort study of term women with singleton, vertex-presenting fetuses who presented with PROM between July 2016 and June 2017 and were eligible for outpatient expectant management (n = 166). The primary outcomes were time from PROM to delivery and time from admission to delivery. Maternal and neonatal outcomes were also compared between groups. Multivariable linear regressions were used to assess time differences between groups, adjusting for known maternal and pregnancy characteristics.

Results Compared with admitted patients, women managed expectantly at home had significantly longer PROM to delivery intervals (median 29.2 vs. 17 hours, p < 0.001), but were more likely to deliver within 24 hours of admission (95.1 vs. 82.9%, p = 0.004). In the adjusted analysis, PROM to delivery was 7 hours longer (95% confidence interval [CI]: 3.9–10.0) and admission to delivery was 5.3 hours shorter (95% CI: 2.8–7.7) in the outpatient expectant management cohort. There were no differences in secondary outcomes.

Conclusion Outpatient management of term PROM is associated with longer PROM to delivery intervals, but shorter admission to delivery intervals.

Note

This study was presented as a poster at the ACOG Annual Meeting in Nashville, TN, on May 3, 2019.




Publication History

Received: 17 May 2019

Accepted: 28 October 2019

Article published online:
31 December 2019

© 2019. Thieme. All rights reserved.

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