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Synthesis 2020; 52(10): 1531-1540
DOI: 10.1055/s-0039-1691599
DOI: 10.1055/s-0039-1691599
paper
Catalyst- and Solvent-Free Synthesis of α-Amino Polyfluoroalkylphosphonates from Bis(fluoroalkyl) Phosphonates and Aldimines
This work has been approved by plans for research projects at the IPC RAS State Registration No. AAAA-A16-116112510005-7.Further Information
Publication History
Received: 12 December 2019
Accepted after revision: 19 January 2020
Publication Date:
13 February 2020 (online)
Abstract
The catalyst- and solvent-free reaction between bis(fluoroalkyl) phosphonates and aldimines occurs under mild conditions (20–22 °C, 0.25–4 h) to afford a new family of α-amino polyfluoroalkylphosphonates in up to quantitative yields.
Key words
bis(fluoroalkyl) phosphonates - aldimines - catalyst-free - solvent-free - α-amino polyfluoroalkylphosphonatesSupporting Information
- Supporting information for this article is available online at https://doi.org/10.1055/s-0039-1691599.
- Supporting Information
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