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Thromb Haemost 1995; 73(02): 325
DOI: 10.1055/s-0038-1653773
Letter to the Editor
Schattauer GmbH Stuttgart

Effect of Factor VII Genotype on Response to Warfarin Treatment

Anne Lane
1   University College London, Department of Medicine, The Rayne Institute, London
,
Fiona Green
1   University College London, Department of Medicine, The Rayne Institute, London
,
Steve Humphries
1   University College London, Department of Medicine, The Rayne Institute, London
,
Vera Ruddock
2   MRC Epidemiology and Medical Care Unit, Wolfson Institute of Preventive Medicine, The Medical College of St Bartholomew’s Hospital, London, UK
,
Tom Meade
2   MRC Epidemiology and Medical Care Unit, Wolfson Institute of Preventive Medicine, The Medical College of St Bartholomew’s Hospital, London, UK
› Author Affiliations
Further Information

Publication History

Received 08 August 1994

Accepted after revision 10 November 1994

Publication Date:
09 July 2018 (online)

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  • References

  • 1 Meade TW, Ruddock V, Stirling Y, Chakrabarti R, Miller GJ. Fibrinolytic activity, clotting factors, and long-term incidence of ischaemic heart disease in the Northwick Park Heart Study. Lancet 1993; 342: 1076-1079
    CrossrefPubMedGoogle Scholar
  • 2 Green F, Kelleher C, Temple A, Meade T, Humphries SE. A common genetic polymorphism associated with lower coagulation factor VII levels in healthy individuals. Arteriosclerosis Thrombosis 1991; 11 (03) 540-546
    CrossrefPubMedGoogle Scholar
  • 3 Lane A, Cruickshank J, Mitchell J, Henderson A, Humphries S, Green F. Genetic and environmental determinants of factor VII coagulant activity in ethnic groups at differing risk of coronary heart disease. Atherosclerosis 1992; 94: 43-50
    CrossrefPubMedGoogle Scholar
  • 4 Humphries S, Lane A, Green F, Cooper J, Miller GJ. Factor Vile coagulant activity and antigen levels and thrombotic potential in healthy men are determined by interaction between factor VII genotype and plasma triglyceride concentration. Arteriosclerosis Thrombosis 14: 193-198
    PubMedGoogle Scholar
  • 5 Meade T, Wilkes H, Stirling Y, Brennan PJ, Kelleher C, Browne W. Randomized controlled trial of low dose warfarin in the primary prevention of ischaemic heart disease in men at high risk: design and pilot study. Eur Heart J 1988; 9: 836-843
    CrossrefPubMedGoogle Scholar