Thromb Haemost 1980; 44(01): 047
DOI: 10.1055/s-0038-1650080
Letter of the Editor
Schattauer GmbH Stuttgart

Relationship between Low Affinity Platelet Factor 4 (LA-PF4) and β-Thromboglobulin (βTG)

Dr. Stefan Niewiarowski
Specialized Center for Thrombosis Research Temple University Health Sciences Philadelphia, Pa. 19140, U.S.A.
› Author Affiliations
Further Information

Publication History

Received 29 May 1980

Accepted 20 June 1980

Publication Date:
26 July 2018 (online)

 
  • References

  • 1 Niewiarowski S, Rucinski P, Budzynski AZ. Low affinity platelet factor 4 and high affinity platelet factor 4 – two antiheparin factors secreted by human platelets. Thromb Haemostas 1980; 42: 1679-1680
  • 2 Begg S, Pepper DS, Chesterman CN, Morgan JF. Complete covalent structure of human β-thromboglobulin. Biochemistry 1978; 17: 1739-1744
  • 3 Rucinski B, Niewiarowski S, James P, Walz DA, Budzynski Z. Antiheparin proteins secreted by human platelets. Purification, characterization and radioimmunoassay. Blood 1979; 53: 47-62
  • 4 Niewiarowski S, Walz DA, James P, Rucinski B, Kueppers F. Identification and separation of secreted platelet proteins by isoelectric focusing. Evidence that low affinity platelet factor 4 is converted to β thromboglobulin by limited proteolysis. Blood 1980; 55: 453
  • 5 Holt JC, Niewiarowski S. Conversion of low affinity platelet factor 4 to β-thromboglobulin by plasmin and trypsin. Biochim Biophys Acta 1980 in press
  • 6 Moore S, Pepper DS. Identification of a platelet specific release product – β thromboglobulin. In Platelet Physiology. ed. Gordon JL. Elsevier/North Holland, Biomedical Press Amsterdam: 1976. p. 293
  • 7 Paul D, Niewiarowski S, Varma KG, Rucinski B, Rucker S, Lange E. Human platelet basic protein associated with antiheparin and mitogenic activities: purification and partial characterization. Proc Natl Acad Sci USA 1980 in press
  • 8 Guzzo J, Niewiarowski S, Musial J, Bastl C, Grossman RA, Rao AK, Berman I, Paul D. Secreted platelet proteins with antiheparin and mitogenic activities in chronic renal failure. J Lab Qin Med 1980; 96: 102-114