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Thromb Haemost 1972; 27(02): 278-291
DOI: 10.1055/s-0038-1649367
Originalarbeiten – Original Articles – Travaux Originaux
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The Effect of Alpha- and Beta-Receptor Blocking Agents on Collagen-Induced Platelet Release Reaction (A Comparison with ADP-Induced Release)

P Kubisz
1   Hemostasis Laboratory, Departmental Hospital, Čadca, Czechoslovakia
,
J Suranova
1   Hemostasis Laboratory, Departmental Hospital, Čadca, Czechoslovakia
› Author Affiliations
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Publication History

Publication Date:
29 June 2018 (online)

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Summary

The mechanism of the platelet release reaction, induced by collagen, is in certain respects different from that of ADP. Besides other facts, the PF 4 release and the availability of PF 3 and APh are not influenced by the concentrations of alpha or beta-receptor blocking agents which clearly interfere with the ADP-induced release.

The possible role of thrombosthenin (or its alpha-receptors in the participation of the release reaction is discussed.

 

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