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Thromb Haemost 1978; 39(01): 012-021
DOI: 10.1055/s-0038-1646119
Original Article
Schattauer GmbH Stuttgart

A Rapid Turbidimetric Determination of Fibrinogen Degradation Products (FDP)

H W Verbruggen
The Division of Haematology, Department Internal Medicine, University of Nijmegen, The Netherlands
,
J M C Wessels
The Division of Haematology, Department Internal Medicine, University of Nijmegen, The Netherlands
› Author Affiliations
Further Information

Publication History

Received 06 June 1975

Accepted 24 June 1977

Publication Date:
12 July 2018 (online)

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Summary

A rapid and simple turbidimetric determination of fibrinogen degradation products is described. This method is based on the increase of the turbidity due to the formation of precipitating antigen-antibody complexes after addition of rabbit antihuman fibrinogen antiserum to human serum. The increase in turbidity correlates very well with results obtained with the haemagglutination inhibition technique and has the advantage of a more objective quantitation. The reproducibility appears to be quite good. The turbidimetric method is independent of the colour of serum samples.

 

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