Localized histiocytic sarcoma in a dog: an uncommon diagnosis in forelimb lameness

M. Bass; O. Gardelle; P. Grest; C. Bernasconi

doi:10.1055/s-0038-1632793

Veterinary and Comparative Orthopaedics and Traumatology, Inhaltsverzeichnis

Vet Comp Orthop Traumatol 2004; 17(01): 48-52
DOI: 10.1055/s-0038-1632793

Case Report

Schattauer GmbH

Localized histiocytic sarcoma in a dog: an uncommon diagnosis in forelimb lameness

M. Bass

¹Clinic for Small Animal Surgery, Faculty of Veterinary Science, University of Zurich, Switzerland

,

O. Gardelle

²Section for Diagnostic Imaging, Faculty of Veterinary Science, University of Zurich, Switzerland

,

P. Grest

³Department of Veterinary Pathology, Faculty of Veterinary Science, University of Zurich, Switzerland

,

C. Bernasconi

⁴Centro Veterinario Airone, Morbio Inferiore, Switzerland

› Institutsangaben

Abstract

Summary

The clinical, ultrasonographic, arthrographic and histopathological aspects of a localized histiocytic sarcoma in the tendon sheath of the biceps brachii muscle in a Flat-Coated Retriever are described. An eight-year-old female Flat-Coated Retriever was referred for evaluation of chronic forelimb lameness. The orthopaedic examination revealed a painful shoulder joint. Ultrasonographic evaluation revealed distention of the tendon sheath of the biceps brachii muscle and the presence of multiple, hyperechoic structures in the distal portion of the sheath. The histological and immunohistochemical diagnosis of a biopsy taken during surgical exploration of the shoulder joint was histiocytic sarcoma. Palliative treatment with corticosteroids was administered but the dog was euthanized at the owner’s request four months following diagnosis due to progressing lameness. Post-mortem examination confirmed the diagnosis of histiocytic sarcoma without any evidence of metastases.

Keywords

Localized histiocytic sarcoma - tendon sheath - FlatCoated Retriever

Volltext

Referenzen

References
1 Affolter VK, Moore PF. Canine cutaneous and systemic histiocytosis: Reactive histiocytosis of dermal dendritic cells NANA. Am J Dermatopathol 2000; 22: 40-8.
2 Affolter VK, Moore PF. Localized and disseminated histiocytic sarcoma of dendritic cell origin in dogs. Vet Pathol 2002; 39: 74-83.
3 Campbell JR. Shoulder lameness in the dog. J Small Anim Pract 1968; 09: 189-98.
4 Craig LE, Julian ME, Ferracone JD. The diagnosis and prognosis of synovial tumors in dogs: 35 cases. Vet Pathol 2002; 39: 66-73.
5 Favara BE, Feller AC, Pauli M, Jaffe ES, Weiss LM, Arico M, Bucsky P, Egeler RM, Elinder G, Gadner H, Gresik M, Hentner JI, Imashuku S, Janka-Schaub G, Jaffe R, Ladisch S, Nezelof C, Pritchard J. Contemporary classification of histiocytic disorders. The WHO Committee on Histiocytic/Reticulum Cell Proliferations. Reclassification Working Group of the Histiocyte Society. Med Pediatr Oncol 1997; 29: 157-66.
6 Feldman EC. Hyperadrenocorticism. In: Ettinger SJ, Feldman EC. (eds). Textbook of Veterinary Internal Medicine. Vol. 2. Philadelphia: W.B. Saunders; 2000: 1460-88.
7 Hayden DW, Waters DJ, Burke BA, Manivel JC. Disseminated malignant histiocytosis in a golden retriever: clinicopathologic, ultrastructural, and immunohistochemical findings. Vet Pathol 1993; 30: 256-64.
8 Kerlin RL, Hendrick MJ. Malignant fibrous histicytoma and malignant histiocytosis in the dog – convergent or divergent phenotypic differentiation?. Vet Pathol 1996; 33: 713-6.
9 Kramer M, Gerwing M, Sheppard C, Schimke E. Ultrasonography for the diagnosis of the tendon sheath of the biceps brachii muscle. Vet Surg 2001; 30: 64-71.
10 Leveille-Webster CR. Laboratory diagnosis of hepatobiliary disease. In: Ettinger SJ, Feldman EC. (eds). Textbook of Veterinary Internal Medicine. Vol. 2. Philadelphia: W.B. Saunders; 2000: 1277-93.
11 MacDonald JM. Glucocorticoid Therapy. In: Ettinger SJ, Feldman EC. (eds). Textbook of Veterinary Internal Medicine. Vol. 1. Philadelphia: W.B. Saunders; 2000: 307-17.
12 MacEwen EG, Withrow SJ. Soft tissue sarcomas. In: Withrow SJ, MacEwen EG. (eds). Small Animal Clinical Oncology. Philadelphia: W.B. Saunders; 2001: 281-304.
13 MacEwen EG, Withrow SJ. Histiocytic disorders. In: Withrow SJ, MacEwen EG. (eds). Small Animal Clinical Oncology. Philadelphia: W.B. Saunders; 2001: 667-71.
14 Moore PF, Rosin A. Malignant histiocytosis of Bernese mountain dogs. Vet Pathol 1986; 23: 1-10.
15 Ogilvie GK, Moore AS. Synovial cell sarcoma in dogs. In: Managing the Veterinary Cancer Patient. Veterinary Learning Systems. 1996: 467-8.
16 Paterson S, Boydell P, Pike R. Systemic histicytosis in the Bernese mountain dog. J Small Anim Pract 1995; 36: 233-6.
17 Visonneau S, Cesano A, Tran T, Jeglum KA, Santoli D. Successful treatment of canine malignant histiocytosis with the human major histocompatibility complex nonrestricted cytotoxic T-cell line TALL-104. Cancer Res 1997; 03: 1789-97.