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Nuklearmedizin 1987; 26(04): 167-171
DOI: 10.1055/s-0038-1628883
Review Articles
Schattauer GmbH

Accuracy and Reproducibility of the Assessment of the Global Ejection Fraction Using 195mAu and a Single-Crystal Digital Gamma Camera: Influence of Collimator Design

Genauigkeit und Reproduzierbarkeit der Beurteilung der globalen Ejektionsfraktion mit 195m Au und einer Einkristall-Digital-Gamma-Kamera: Einfluss des Kollimator-Designs
G. Zatta
*   From the Nuclear Medicine Department, Milan, Italy
,
G. L. Tarolo
*   From the Nuclear Medicine Department, Milan, Italy
,
M. Gallazzi
*   From the Nuclear Medicine Department, Milan, Italy
,
A. De Agostini
*   From the Nuclear Medicine Department, Milan, Italy
,
A. Albertini
**   Istituto di Scienze Mediche Bassini, Milan, Italy
,
Maria Radice
**   Istituto di Scienze Mediche Bassini, Milan, Italy
,
D. Alberti
***   Milan University School of Medicine and the CIBA Foundation, Milan, Italy
› Author Affiliations
Further Information

Publication History

Received: 24 February 1987

Publication Date:
04 February 2018 (online)

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A sequence of RAO first-pass studies (first with 99mTc and then twice with 195mAu) was performed in 18 normal volunteers and in 12 CAD patients using two different types of collimator for medium energy: a standard collimator (MEMS) and a special high-sensitivity collimator (MEHS). The following data were compared: the peak count rate, the net LV end-diastolic counts and the LVEF. Using MEMS the end-diastolic counts acquired were so low (12% of 99mTc average value) that EF standard deviation had a mean value of 0.061 (range 0.045-0.081). With MEHS the following results were obtained: 1. the peak count rate and LV net end-diastolic counts with 195mAu were 55% and 50% respectively, of 99mTc values; 2. a good correlation was shown between LVEF values either with 99mTc and 195mAu (r =.97), or with 195mAu sequential studies (r =.98).

Zusammenfassung

Erste-Passage-Untersuchungen in RAO (zunächst mit 99mTc, dann zweimal mit 195mAu) wurden bei 18 Gesunden und bei 12 Patienten mit koronarer Herzkrankheit durchgeführt. Hierbei wurden zwei unterschiedliche Mittelenergie-Kollimatoren eingesetzt: ein Standard-Kollimator (MEMS) und ein spezieller hochempfindlicher Kollimator (MEHS). Folgende Daten wurden verglichen: die maximale Zählrate, die linksventrikuläre enddiastolische Zählrate (netto) und die linksventrikuläre Auswurffraktion. Mit MEMS waren die enddiastolischen Zählraten so niedrig (12% des Technetium-Wertes), daß die Streubreite der Auswurffraktion einen Mittelwert von 0,061 (Streubereich 0.045-0.081) aufwies. Für den MEHS betrugen maximale Zählrate bzw. linksventrikuläre enddiastolische Zählrate mit 195mAu 55% bzw. 50% der Technetium-Werte. Für die Werte der Auswurffraktion ergab sich eine gute Korrelation (99mTc vs 195mAu: r = 0.97). Die 195mAu-Werte waren exzellent reproduzierbar (r = 0.98).

 

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