Thromb Haemost 2001; 85(03): 566-567
DOI: 10.1055/s-0037-1615628
Letters to the Editor
Schattauer GmbH

No Association between the R2 Factor V Gene and Acute Coronary Events

N. Ameziane
1   Service d’Hématologie et d’Immunologie, Hôpital Louis Mourier, Colombes
,
D. Lebret
1   Service d’Hématologie et d’Immunologie, Hôpital Louis Mourier, Colombes
,
A. Combe
1   Service d’Hématologie et d’Immunologie, Hôpital Louis Mourier, Colombes
,
M.-C. Aumont
2   Service de Cardiologie, Hôpital Bichat-Claude Bernard AP-HP, Paris, France
,
D. de Prost
1   Service d’Hématologie et d’Immunologie, Hôpital Louis Mourier, Colombes
› Author Affiliations
Further Information

Publication History

Received 18 September 2000

Accepted after resubmission 14 December 2000

Publication Date:
08 December 2017 (online)

 

 
  • References

  • 1 Bernardi F, Faioni EM, Castoldi E, Lunghi B, Castaman G, Sacchi E, Mannucci PM. A factor V genetic component differing from factor V R506Q contributes to the activated protein C resistance phenotype. Blood 1997; 90: 1552-7.
  • 2 Lunghi B, Iacoviello L, Gemmati D, Dilasio MG, Castoldi E, Pinotti M, Castaman G, Redaelli R, Mariani G, Marchetti G, Bernardi F. Detection of new polymorphic markers in the factor V gene: Association with factor V levels in plasma. Thromb Haemost 1996; 75: 45-8.
  • 3 Castoldi E, Rosing J, Girelli D, Hoekema L, Lunghi B, Mingozzi F, Ferraresi P, Friso S, Corrocher R, Tans G, Bernardi F. Mutations in the R2 FV gene affect the ratio between the two FV isoforms in plasma. Thromb Haemost 2000; 83: 362-5.
  • 4 Castoldi E, Rosing J, Lunghi B, Hoekema L, Girelli D, Mingozzi F, Ferraresi P, Friso S, Corrocher R, Tans G, Bernardi F. Factor V gene mutations (R2 gene) are associated with coronary artery disease in elderly people. Thromb Haemost 1999; 82 suppl. 509 (abstract).
  • 5 Moatti D, Seknadji P, Galand C, Poirier O, Fumeron F, Desprez S, Garbarz M, Dhermy D, Arveiler D, Evans A, Luc G, Ruidavets JB, Ollivier V, Hakim J, Aumont MC, de Prost D. Polymorphisms of the tissue factor pathway inhibitor (TFPI) gene in patients with acute coronary syndromes and in healthy subjects. Impact of the V264M substitution on plasma levels of TFPI. Arterioscler Thromb Vasc Biol 1999; 19: 862-9.
  • 6 Alhenc-Gelas M, Nicaud V, Gandrille S, van Dreden P, Amiral J, Aubry M-L, Fiesinger JN, Emmerich J, Aiach M. The factor V gene A4070G mutation and the risk of venous thrombosis. Thromb Haemost 2000; 81: 193-7.