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Synthesis 2020; 52(10): 1541-1543
DOI: 10.1055/s-0037-1610752
DOI: 10.1055/s-0037-1610752
paper
The Dianion of Dehydroacetic Acid: A Direct Synthesis of Pogopyrone A
We thank KeyPlex for partial support of this work.Further Information
Publication History
Received: 07 January 2020
Accepted after revision: 28 January 2020
Publication Date:
12 February 2020 (online)
Abstract
Dehydroacetic acid was converted into a silyl enol ether and titanium enolate. These reacted effectively with aldehydes and N-bromosuccinimide. Oxidation of the adduct with benzaldehyde afforded pogopyrone A in excellent overall yield.
Supporting Information
- Supporting information for this article is available online at https://doi.org/10.1055/s-0037-1610752.
- Supporting Information
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