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Journal of Pediatric Neurology 2016; 14(04): 146-150
DOI: 10.1055/s-0036-1592083
Original Article
Georg Thieme Verlag KG Stuttgart · New York

Evaluation of Children with Subacute Sclerosing Panencephalitis Using Magnetic Resonance Spectroscopy

Berna Kırhan
1   Department of Pediatrics, Harran University Medical Faculty, Sanliurfa, Turkey
,
Mahmut Abuhandan
1   Department of Pediatrics, Harran University Medical Faculty, Sanliurfa, Turkey
,
Hasan Cece
2   Department of Radiology, Harran University Medical Faculty, Sanliurfa, Turkey
,
Mustafa Calik
3   Department of Pediatric Neurology, Harran University Medical Faculty, Sanliurfa, Turkey
,
Abdurrahman Sonmezler
4   Department of Neurology, Harran University Medical Faculty, Sanliurfa, Turkey
,
Nihat Kilicaslan
2   Department of Radiology, Harran University Medical Faculty, Sanliurfa, Turkey
,
Akın İscan
3   Department of Pediatric Neurology, Harran University Medical Faculty, Sanliurfa, Turkey
› Author Affiliations
Further Information

Publication History

18 April 2016

22 July 2016

Publication Date:
14 September 2016 (online)

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Abstract

This study aimed to evaluate metabolite ratios in the brain parenchyma of patients with subacute sclerosing panencephalitis (SSPE) using magnetic resonance spectroscopy (MRS). The study compared 32 children diagnosed with SSPE with a control group of 20 healthy children. Comparisons were made between the study and control groups and between children who had various stages of the disease, as well as between MRS values obtained from the frontal subcortical white matter and parieto-occipital white matter regions by multivoxel MRS imaging. MRS may make a contribution to diagnosis and follow-up of children with SSPE as findings reflecting neuronal loss may be revealed by this imaging technique.

Keywords

SSPE - MRS - clinical stages - children
 

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