Copper Triflate Catalyzed Oxidative α-Allylation of Glycine Derivatives

Abstract

Copper triflate catalyzed oxidative C–H functionalization of glycine derivatives with allyltributyltin has been established using oxygen or tert-butyl hydroperoxide as oxidant. Various glycine esters and glycine amides were suitable substrates for this oxidative allylation reaction and afforded the desired homoallylic amines in moderate to good yields.

Key words

copper triflate - glycine derivatives - allylation - homoallylic amines - oxygen - TBHP

• References and Notes

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