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Synlett 2016; 27(02): 304-308
DOI: 10.1055/s-0035-1560707
DOI: 10.1055/s-0035-1560707
letter
An Azide-Functionalized Nitronyl Nitroxide Radical: Synthesis, Characterization and Staudinger–Bertozzi Ligation Reactivity
Further Information
Publication History
Received: 31 July 2015
Accepted after revision: 15 September 2015
Publication Date:
14 October 2015 (online)
Abstract
An azide-functionalized nitronyl nitroxide was synthesized and its reactivity towards the Staudinger–Bertozzi ligation was explored. Whereas a model reaction in solution showed the conversion of nitronyl nitroxide to an imino nitroxide radical, the same reaction at the interface of gold nanoparticles allowed for successful covalent incorporation of the nitronyl nitroxide radical onto the nanoparticles.
Key words
gold nanoparticles - stable radicals - nitronyl nitroxides - bioorthogonal chemistry - EPR spectroscopy - X-ray spectroscopySupporting Information
- Supporting information for this article is available online at http://dx.doi.org/10.1055/s-0035-1560707.
- Supporting Information
Primary Data
- Primary data for this article are available online at http://www.thieme-connect.com/products/ejournals/journal/10.1055/s-00000083 and can be cited using the following DOI: 10.4125/pd0072th.
- Primary Data
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References and Notes
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