Thorac Cardiovasc Surg 2016; 64(04): 316-322
DOI: 10.1055/s-0035-1549357
Original Cardiovascular
Georg Thieme Verlag KG Stuttgart · New York

Our Short-Term Results with Percutaneous Mechanical Thrombectomy for Treatment of Acute Deep Vein Thrombosis

Berkan Ozpak
1   Department of Cardiovascular Surgery, Tekirdag State Hospital, Tekirdag, Turkey
,
Gokhan Ilhan
2   Department of Cardiovascular Surgery, Recep Tayip Erdogan University, Rize, Turkey
,
Barcin Ozcem
3   Department of Cardiovascular Surgery, Near East University, Lefkosa, Cyprus
,
Hakan Kara
4   Department of Cardiovascular Surgery, Ada Hospital, Giresun, Turkey
› Author Affiliations
Further Information

Publication History

25 November 2014

12 February 2015

Publication Date:
19 June 2015 (online)

Abstract

Background Anticoagulant treatment is recently being replaced by more aggressive endovascular modalities in the management of acute deep vein thrombosis (DVT). These techniques have been promoted to improve thrombus removal, prolong venous patency, prevent venous insufficiency, and reduce post thrombotic syndrome. The aim of the present study is to overview the short-term results of percutaneous mechanical thrombectomy (PMT) for acute DVT.

Methods This retrospective study is based on data from 21 acute DVT patients treated with PMT in the cardiovascular surgery department of a tertiary care center. The average age of patients was 48.76 (range: 27–69). Retrievable inferior vena cava (IVC) filters were administered via right subclavian vein or contralateral femoral vein and withdrawn after PMT procedure. Low-molecular-weight heparin (LMWH) was used for anticoagulation in the first 10 days postoperatively.

Results Venous patency was restored in 20/21 patients (95%) at first month, and in 18/21 patients (85%) at sixth month. Valvular competency was preserved in 16 patients (76%). Balloon angioplasty with or without stent implantation was performed in three patients with stenosis in femoral or iliac veins.

Conclusion In conclusion, PMT is a safe and effective treatment modality that can be used alone in the treatment of acute DVT of lower extremities in selected cases. Further controlled trials on larger series and reports on long-term results are warranted to document the actual therapeutic potential and safety this endovascular procedure.

 
  • References

  • 1 Hill SL, Martin D, Evans P. Massive venous thrombosis of the extremities. Am J Surg 1989; 158 (2) 131-135
  • 2 Akesson H, Brudin L, Dahlström JA, Eklöf B, Ohlin P, Plate G. Venous function assessed during a 5 year period after acute ilio-femoral venous thrombosis treated with anticoagulation. Eur J Vasc Surg 1990; 4 (1) 43-48
  • 3 Delis KT, Bountouroglou D, Mansfield AO. Venous claudication in iliofemoral thrombosis: long-term effects on venous hemodynamics, clinical status, and quality of life. Ann Surg 2004; 239 (1) 118-126
  • 4 O'Donnell Jr TF, Browse NL, Burnand KG, Thomas ML. The socioeconomic effects of an iliofemoral venous thrombosis. J Surg Res 1977; 22 (5) 483-488
  • 5 Kearon C. Natural history of venous thromboembolism. Circulation 2003; 107 (23) (Suppl. 01) I22-I30
  • 6 Peden E, Zhou W, Bush RL, Lumsden AB, Lin PH. The case for thrombolysis for iliofemoral venous thrombosis. Semin Vasc Surg 2005; 18 (3) 139-147
  • 7 Mohr DN, Silverstein MD, Heit JA, Petterson TM, O'Fallon WM, Melton LJ. The venous stasis syndrome after deep venous thrombosis or pulmonary embolism: a population-based study. Mayo Clin Proc 2000; 75 (12) 1249-1256
  • 8 Comerota AJ, Gravett MH. Iliofemoral venous thrombosis. J Vasc Surg 2007; 46 (5) 1065-1076
  • 9 Douketis JD, Crowther MA, Foster GA, Ginsberg JS. Does the location of thrombosis determine the risk of disease recurrence in patients with proximal deep vein thrombosis?. Am J Med 2001; 110 (7) 515-519
  • 10 Vedantham S, Thorpe PE, Cardella JF , et al. Quality improvement guidelines for the treatment of lower extremity deep vein thrombosis with use of endovascular thrombus removal. J Vasc Interv Radiol 2006; 17 (3) 435-447 , quiz 448
  • 11 Delomez M, Beregi JP, Willoteaux S , et al. Mechanical thrombectomy in patients with deep venous thrombosis. Cardiovasc Intervent Radiol 2001; 24 (1) 42-48
  • 12 Kasirajan K, Gray B, Ouriel K. Percutaneous AngioJet thrombectomy in the management of extensive deep venous thrombosis. J Vasc Interv Radiol 2001; 12 (2) 179-185
  • 13 Vedantham S, Vesely TM, Parti N, Darcy M, Hovsepian DM, Picus D. Lower extremity venous thrombolysis with adjunctive mechanical thrombectomy. J Vasc Interv Radiol 2002; 13 (10) 1001-1008
  • 14 Arko FR, Davis III CM, Murphy EH , et al. Aggressive percutaneous mechanical thrombectomy of deep venous thrombosis: early clinical results. Arch Surg 2007; 142 (6) 513-518 , discussion 518–519
  • 15 Tsai J, Georgiades CS, Hong K, Kim HS. Presumed pulmonary embolism following power-pulse spray thrombectomy of upper extremity venous thrombosis. Cardiovasc Intervent Radiol 2006; 29 (4) 678-680
  • 16 Hirsh J, Guyatt G, Albers GW, Harrington R, Schünemann HJ ; American College of Chest Physicians. Executive summary: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines (8th Edition). Chest 2008; 133 (6, Suppl): 71S-109S
  • 17 Kearon C, Kahn SR, Agnelli G, Goldhaber S, Raskob GE, Comerota AJ ; American College of Chest Physicians. Antithrombotic therapy for venous thromboembolic disease: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines (8th Edition). Chest 2008; 133 (6, Suppl): 454S-545S
  • 18 Snow V, Qaseem A, Barry P , et al; American College of Physicians; American Academy of Family Physicians Panel on Deep Venous Thrombosis/Pulmonary Embolism. Management of venous thromboembolism: a clinical practice guideline from the American College of Physicians and the American Academy of Family Physicians. Ann Intern Med 2007; 146 (3) 204-210
  • 19 Prandoni P, Lensing AW, Cogo A , et al. The long-term clinical course of acute deep venous thrombosis. Ann Intern Med 1996; 125 (1) 1-7
  • 20 van Dongen CJ, Prandoni P, Frulla M, Marchiori A, Prins MH, Hutten BA. Relation between quality of anticoagulant treatment and the development of the postthrombotic syndrome. J Thromb Haemost 2005; 3 (5) 939-942
  • 21 Kahn SR, Shrier I, Julian JA , et al. Determinants and time course of the postthrombotic syndrome after acute deep venous thrombosis. Ann Intern Med 2008; 149 (10) 698-707
  • 22 Mewissen MW, Seabrook GR, Meissner MH, Cynamon J, Labropoulos N, Haughton SH. Catheter-directed thrombolysis for lower extremity deep venous thrombosis: report of a national multicenter registry. Radiology 1999; 211 (1) 39-49
  • 23 Gogalniceanu P, Johnston CJ, Khalid U , et al. Indications for thrombolysis in deep venous thrombosis. Eur J Vasc Endovasc Surg 2009; 38 (2) 192-198
  • 24 Ouriel K, Gray B, Clair DG, Olin J. Complications associated with the use of urokinase and recombinant tissue plasminogen activator for catheter-directed peripheral arterial and venous thrombolysis. J Vasc Interv Radiol 2000; 11 (3) 295-298
  • 25 Nazir SA, Ganeshan A, Nazir S, Uberoi R. Endovascular treatment options in the management of lower limb deep venous thrombosis. Cardiovasc Intervent Radiol 2009; 32 (5) 861-876
  • 26 McLafferty RB. Endovascular management of deep venous thrombosis. Perspect Vasc Surg Endovasc Ther 2008; 20 (1) 87-91
  • 27 Gandini R, Maspes F, Sodani G, Masala S, Assegnati G, Simonetti G. Percutaneous ilio-caval thrombectomy with the Amplatz device: preliminary results. Eur Radiol 1999; 9 (5) 951-958
  • 28 Rao AS, Konig G, Leers SA , et al. Pharmacomechanical thrombectomy for iliofemoral deep vein thrombosis: an alternative in patients with contraindications to thrombolysis. J Vasc Surg 2009; 50 (5) 1092-1098
  • 29 Lee KH, Han H, Lee KJ , et al. Mechanical thrombectomy of acute iliofemoral deep vein thrombosis with use of an Arrow-Trerotola percutaneous thrombectomy device. J Vasc Interv Radiol 2006; 17 (3) 487-495
  • 30 Sharafuddin MJA, Hicks ME. Current status of percutaneous mechanical thrombectomy. Part I. General principles. J Vasc Interv Radiol 1997; 8 (6) 911-921
  • 31 Sharafuddin MJA, Hicks ME. Current status of percutaneous mechanical thrombectomy. Part II. Devices and mechanisms of action. J Vasc Interv Radiol 1998; 9 (1, Pt 1) 15-31
  • 32 Kibbe MR, Ujiki M, Goodwin AL, Eskandari M, Yao J, Matsumura J. Iliac vein compression in an asymptomatic patient population. J Vasc Surg 2004; 39 (5) 937-943
  • 33 O'Sullivan GJ, Semba CP, Bittner CA , et al. Endovascular management of iliac vein compression (May-Thurner) syndrome. J Vasc Interv Radiol 2000; 11 (7) 823-836