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Planta Med 2014; 80(12): 974-977
DOI: 10.1055/s-0034-1382902
Biological and Pharmacological Activity
Original Papers
Georg Thieme Verlag KG Stuttgart · New York

Effect of Quercetin-3-O-Sambubioside Isolated from Eucommia ulmoides Male Flowers on Spontaneous Activity and Convulsion Rate in Mice

Xin Li
1   College of Food and Bioengineering, Henan University of Science and Technology, Luoyang, China
,
Lipeng Yang
1   College of Food and Bioengineering, Henan University of Science and Technology, Luoyang, China
,
Shaoyang Liu
2   Food Engineering Department, Luohe Medical College, Luohe, China
,
Dongqing Fei
3   School of Pharmacy, Lanzhou University, Lanzhou, China
,
Min Zhang
1   College of Food and Bioengineering, Henan University of Science and Technology, Luoyang, China
,
Yuxian Zhang
1   College of Food and Bioengineering, Henan University of Science and Technology, Luoyang, China
› Author Affiliations
Further Information

Publication History

received 22 December 2013
revised 19 June 2014

accepted 20 June 2014

Publication Date:
06 August 2014 (online)

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Abstract

The purpose of this study was to evaluate the effects of quercetin-3-O-sambubioside on the neural system. Quercetin-3-O-sambubioside is a monomeric compound found in Eucommia ulmoides male flowers from which it was extracted using a system solvent method. In the experiments, spontaneous activity and convulsion rate in mice were recorded, and quercetin-3-O-sambubioside shows eminent effects similar to nikethamide on increasing spontaneous activity and stimulating the nerve center to enhance excitement. These findings are indicative of the powerful ability of quercetin-3-O-sambubioside to promote the stimulation of the nerve center.

Key words

Eucommia ulmoides - Eucommiaceae - quercetin-3-O-sambubioside - neural excitation - excitement

Supporting Information

 

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